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 CSE 527, Au '04: Reading Assignment #2, Due: 10/15/04
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Microarray Reading

Find and read a good paper on microarrays, preferably one showing a combination of biological application and computational analysis. Email me a link and/or citation to the paper you read, together with a few sentences about it. E.g., highlight one or two things from it that you found especially interesting or surprising, either about the biology or computational approaches, critique it from either perspective, and/or suggest a logical extension to the work that would be a good next step.

You may pick a paper from anywhere, including the Chu, et al. paper I talked about in class. The links on the Homework 1 page may also be useful. Here are others; in particular, the bibliography in 2 below is quite extensive, and 3 identifies some widely cited papers (but hasn't been updated in a year). If you've never used PubMed, I'd recommend it. (In general, I don't recommend CiteSeer for his course; it tends to run a little too far on the CS side of the fence.)

  1. Chu S, DeRisi J, Eisen M, Mulholland J, Botstein D, Brown PO, Herskowitz I. "The transcriptional program of sporulation in budding yeast." Science. 1998 Oct 23;282(5389):699-705.
  2. Bibliography on Microarray Data Analysis http://www.nslij-genetics.org/microarray/
  3. Science Citation analysis on microarray papers using the HISTCITE program by Eugene Garfield

As I did last week, I'll post interesting additions.

Please Note:

To simplify the chore of editing your answers for the web, please format your email as follows: Thanks!


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