All You Need To Know About Enyne Metathesis

Basic Facts You Need To Know

  1. It's a reaction between an alkene and a alkyne.
  2. The product is two alkenes.
  3. The reaction could be intermolecular and intramolecular.
  4. In a ring closing enyne metathesis, five and six membered rings could be easily achieved, whereas seven and eight membered rings are not formed unless the ring has a hetero atom.
  5. Mono substituted alkenes react faster than di- or trisubstituted alkenes.

Mechanism

Mechanism of Enyne Metathesis

This reaction mechanism shown above is an ring closing enyne metathesis.

Synthesis Application

Example of Synthesis Application of Enyne Metathesis

Read more about the synthesis application in this website