Reasons to be pessimistic...
Generate-and-test approach requires one strand of DNA for each candidate solution
- 270 DNA strands of length 1000 is 8 kilograms
DNA processing is slow and error prone
- 1 hour per reaction
- Error-correction adds molecules and steps
- Need to learn to build reliable computers from noisy components
No communication between strands
- No easy way to determine if a tube contains two identical strands
No killer app has been identified yet