CSE 427 Winter 2013
Course Calendar

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January
SundayMondayTuesdayWednesdayThursdayFridaySaturday
06 07 08
10:30-11:50 Lecture
SAV 139
Basics of molecular biology: proteins, DNA, replication
Hunter's primer
Molecular Biology handout
15:00-16:00 OH (PV)
CSE 218
09
17:00 HW0 due
10
10:30-11:50 Lecture
SAV 139
Basics of molecular biology: gene expression and structure
12:30-13:25 OH (MT)
CSE 538
11 12
13 14 15
10:30-11:50 Lecture
SAV 139
Pairwise global alignment
Lectures 3-5 from CSE 527
15:00-16:00 OH (PV)
CSE 218
16 17
10:30-11:50 Lecture
SAV 139
Pairwise local alignment, affine gap penalties
12:30-13:25 OH (MT)
CSE 538
18 19
20 21
Martin Luther King Day
22:00 HW1 due
22
10:30-11:50 Lecture
SAV 139
BLAST
Overview of the BLAST Algorithm
Altschul, S.F., Gish, W., Miller, W., Myers, E.W. & Lipman, D.J. (1990), "Basic local alignment search tool". Journal of Molecular Biology 215:403-410.
15:00-16:00 OH (PV)
CSE 218
23 24
10:30-11:50 Lecture
SAV 139
BLAST statistics; amino acid substitution matrices
Section 6.5 from Ewens and Grant's book
Stephen Altschul's primer
12:30-13:25 OH (MT)
CSE 538
25 26
27 28 29
10:30-11:50 Lecture
SAV 139
Multiple sequence alignment
Lectures 6 from CSE 527
Overview of progressive alignment
15:00-16:00 OH (PV)
CSE 218
30 31
12:30-13:25 OH (MT)
CSE 538
01 02

February
SundayMondayTuesdayWednesdayThursdayFridaySaturday
03
22:00 HW2 due
04 05
10:30-11:50 Lecture
SAV 139
Phylogeny construction
Building phylogenies
15:00-16:00 OH (PV)
CSE 218
06 07
10:30-11:50 Lecture
SAV 139
Markov chains and classification
Markov Models
12:30-13:25 OH (MT)
CSE 538
08 09
10 11 12
10:30-11:50 Lecture
SAV 139
Hidden Markov models
15:00-16:00 OH (PV)
CSE 218
13 14
10:30-11:50 Lecture
SAV 139
Profile HMMs
Profile HMMs
12:30-13:25 OH (MT)
CSE 538
15 16
17 18
Presidents Day
19
10:30-11:50 Lecture
SAV 139
Motif discovery; statistical overrepresentation; MEME
Prediction of sequence motifs
15:00-16:00 OH (PV)
CSE 218
22:00 HW3 due
20 21
10:30-11:50 Lecture
SAV 139
Gibbs sampling; FootPrinter
12:30-13:25 OH (MT)
CSE 538
22 23
24 25 26
10:30-11:50 Lecture
SAV 139
MicroFootPrinter
MEME and Gibbs demo
15:00-16:00 OH (PV)
CSE 218
27 28
10:30-11:50 Lecture
SAV 139
Technical details of profile HMMs
12:30-13:25 OH (MT)
CSE 538
01 02

March
SundayMondayTuesdayWednesdayThursdayFridaySaturday
03 04 05
10:30-11:50 Lecture
SAV 139
Microbiomes
Microbes and You
15:00-16:00 OH (PV)
CSE 218
06 07
10:30-11:50 Lecture
SAV 139
More profile HMMs and microbiomes
12:30-13:25 OH (MT)
CSE 538
08
22:00 HW4 due
09
10 11 12
10:30-11:50 Lecture
SAV 139
Colonization of infant gut
Infant gut microbiome
15:00-16:00 OH (PV)
CSE 218
13 14
10:30-11:50 Lecture
SAV 139
Other directions, Schnapsen
Challenges in computational biology
12:30-13:25 OH (MT)
CSE 538
15 16