CLUSTAL 2.0.10 multiple sequence alignment

Alignment of the 14 proteins whose annotation was "cytochrome ..., subunit III".
* denotes a perfectly conserved column, and : and . denote well conserved columns. 
You will notice some regions of very good conservation among all these proteins. 

Brucella_suis                   MADVHQKNHDYHIIAPSPWPFLSSVGAFVLAIGGIAWMRYINAGELPFFG 50
Brucella_abortus                MADVHQKNHDYHIIAPSPWPFLSSVGAFVLAIGGIAWMRYINAGELPFFG 50
Mesorhizobium_sp.               MADAHAKKHDYHIIDPSPWPFIASVGALVMALGAIAWMKAAQGSSFPVFG 50
Nitrobacter_winogradskyi        MATAQVK-HDYHLVDPSPWPIVGATAAFIMAVGAILWMHHMTAAAPIIFG 49
Homo_sapiens                    ---MTHQSHAYHMVKPSPWPLTGALSALLMTSGLAMWFHFHSMT------ 41
Shewanella_oneidensis           -MTTKHET--YYVPAQSAWPIVGAIGLFLIAFGAGQFVTQLKSGNSGGG- 46
Shewanella_sp.                  -MTTKHET--YYVPAQSAWPIVGAIGLFLIAFGAGHFVHQLKSGASGGG- 46
Burkholderia_phymatum           -MSGQNESPYYFIPHPSRHPISAAVGLLVMLGSFAAWVN----GEPWAP- 44
Mycobacterium_tuberculosis      --------------------------------------------------
Serratia_proteamaculans         --------------------------------------------------
Xylella_fastidiosa              --------------------------------------------------
Francisella_tularensis          --------------------------------------------------
Roseiflexus_castenholzii        --------------------------------------------------
Geobacter_metallireducens       --------------------------------------------------
                                                                                  

Brucella_suis                   LNVVTP--WIFFIGLAIVLYCMFGWWSDTIKEG-HEGHHTRVVSLHLRYG 97
Brucella_abortus                LNVVTP--WIFFIGLAIVLYCMFGWWSDTIKEG-HEGHHTRVVSLHLRYG 97
Mesorhizobium_sp.               IDLAASRFWLFLIGLLIILYTMFSWWSDTIREG-QEGHHTAVVSLHLRYG 99
Nitrobacter_winogradskyi        ------------IGVVGVLYTMASWWADVIREAEHKGDHTRVVQISHRYG 87
Homo_sapiens                    ---------LLMLGLLTNTLTMYQWWRDVTRESTYQGHHTPPVQKGLRYG 82
Shewanella_oneidensis           --------YILFAGIAVILFMLVGWFRTVIQES-MTGLYSHQMDRSFRQG 87
Shewanella_sp.                  --------YILLAGIVVILFMLVGWFRTVIQES-MTGLYSHQMDRSFRQG 87
Burkholderia_phymatum           --------ITALIGLLWLLFTLYHWFGDAISES-EGGMYGKRVDTSFRWS 85
Mycobacterium_tuberculosis      ------------------MTSAVGTSGTAITSR----VHSLNRPNMVSVG 28
Serratia_proteamaculans         ----------------------MSTDTLTNHDAAHAEHGHHDAGETKVFG 28
Xylella_fastidiosa              ----------------------MPIS--TKIDMHNRDHAHHDTGDNTVFG 26
Francisella_tularensis          ------------------------MS--TVTAEHNHHHEHHFDGSKNVFG 24
Roseiflexus_castenholzii        ----------------------MSESS-MIRPHATTAHHTSLGVDNRKLG 27
Geobacter_metallireducens       -----------------------------------MSHQTRKDPAGAKLG 15
                                                                                 .

Brucella_suis                   MIMFIASEVMFFVAWFWAFFDASLFPN---------EVHQVARAEFTGGV 138
Brucella_abortus                MIMFIASEVMFFVAWFWAFFDASLFPN---------EVHQVARAEFTGGV 138
Mesorhizobium_sp.               MIMFIASELMFFVAWFWAFFDASLFPG---------DPSQVSRAEFTGGT 140
Nitrobacter_winogradskyi        MILFITSEVMFFVAWFWAFFNSALFPG---------DPVHVTREALFGGV 128
Homo_sapiens                    MILFITSEVFFFAGFFWAFYHSSLAP-----------------TPQLGGH 115
Shewanella_oneidensis           MSWFIFSEVMFFAAFFGALFYARMFAVPWLGGASNNAMTHEVLWPNFEAV 137
Shewanella_sp.                  MSWFIFSEVMFFAAFFGALFYARMVAVPWLGGASNNAMTHEVLWPHFEAV 137
Burkholderia_phymatum           MSWFIFSEVMFFGAFFGALFYAREIAMHQLG-----SLDYKLIWPDFTAV 130
Mycobacterium_tuberculosis      TIVWLSSELMFFAGLFAFYFSARAQAG---------------------GN 57
Serratia_proteamaculans         FWIYLMSDCILFASLFATYAVLVNGTAG------------GPSGK----- 61
Xylella_fastidiosa              FWVYLMSDCLIFAGLFATYAVLVGATVD------------GPTAK----- 59
Francisella_tularensis          FWIYIMSDCVLFATLFATFAVFHKHTFG------------GPGAQ----- 57
Roseiflexus_castenholzii        VWAFIGSETLFFATLITTYFVFAPVNRA------------RPDFQDP--- 62
Geobacter_metallireducens       MWLFLFTELFLFGGLFLLYGVYLARYHR------------EFAAAG---- 49
                                   :: :: .:*   :                                  

Brucella_suis                   WPPKG-------IEVLDPLH-LPLYNTVILLLSGTTLTWAHHALLHNDRK 180
Brucella_abortus                WPPKG-------IEVLDPLH-LPLYNTVILLLSGTTLTWAHHALLHNDRK 180
Mesorhizobium_sp.               WPPHG-------VEVLDPFH-LPLYNTIILLLSGTTVTWAHHALLENDRK 182
Nitrobacter_winogradskyi        WPPKG-------IQTFDPWH-LPLLNTLILLTSGTTVTWAHHALLNGDRK 170
Homo_sapiens                    WPPTG-------ITPLNPLE-VPLLNTSVLLASGVSITWAHHSLMENNRN 157
Shewanella_oneidensis           WPLLTTPDGTK--TEAMPWNGLPLINTIVLLTSSVTLHFAHISLEKGKRS 185
Shewanella_sp.                  WPLLTTPDGTK--TEAMPWNGLPLVNTIVLLTSSVTLHFAHTSLEKGKRS 185
Burkholderia_phymatum           WPNIGPADLVSHFKSMTPWP-VPTINTALLLSSGATLTVSHHALRDNHRT 179
Mycobacterium_tuberculosis      WPPPP--------TELNLYQAVPVT--LVLIASSFTCQMGVFAAERGDIF 97
Serratia_proteamaculans         --------------DIFDLK-FVLVETFLLLFSSITYGMAMIGMNKGKVG 96
Xylella_fastidiosa              --------------ELFDLK-FVLVETFLLLFSSLTFGFAMIAAHKRHIP 94
Francisella_tularensis          --------------ELFSLP-YVFVETMLLLISSFTFGLAMLNHNSENIN 92
Roseiflexus_castenholzii        -------------REFLDIE-LTTVLASILLASSLTMVLALSASKRGDRR 98
Geobacter_metallireducens       --------------REMHLG-FGTANTVILITSSLLAAMAVTAIQRSGRR 84
                                                            :*: *.     .          

Brucella_suis                   GMITGLAITVALGVLFSCVQAYEYIHAP----FAFKD---------SIYG 217
Brucella_abortus                GMITGLAITVALGVLFSCVQAYEYIHAP----FAFKD---------SIYG 217
Mesorhizobium_sp.               GLVAGLAVTVALGILFSFVQAYEYMHAP----FAFSD---------SIYG 219
Nitrobacter_winogradskyi        GLKWGLILTIALGAIFTCVQAYEYQHAA----FSFAG---------NVYG 207
Homo_sapiens                    QMIQALLITILLGLYFTLLQASEYFESP----FTISD---------GIYG 194
Shewanella_oneidensis           AITLWLGLTILLGIGFLALQVAEYRHAYEEMGLTLTS---------GIYG 226
Shewanella_sp.                  AITLWLGLTILLGISFLALQAEEYSHAYHEMGLTLTS---------GVYG 226
Burkholderia_phymatum           KAIAWLAATLVLGVSFLFLQGFEYFHAYNELNLTLAS---------GVYG 220
Mycobacterium_tuberculosis      GLRRWYVITFLMGLFFVLGQAYEYRNLMSHG-TSIPS---------SAYG 137
Serratia_proteamaculans         SVNTWLFLTFLFGLGFVAMEIYEFHHLIVEG-YGPDR---------SAFL 136
Xylella_fastidiosa              ALYGWLMVTALFGLGFLGMELYEFHHLIQEG-AGPGR---------SAFL 134
Francisella_tularensis          HVIKFLWITFFLGLGFIIMEVHEFYELAIEG-HTWSS---------SAFL 132
Roseiflexus_castenholzii        WFTTWLLATVGLGLAFIGGQVYEFNHLYHEG-LTLSS---------SLFG 138
Geobacter_metallireducens       LVLYLLGGTVLCGAVFLFNKYLEWSDEIGHGIYPGSPRLAAGPPGESVFY 134
                                        *   *  *   :  *: .                    . : 

Brucella_suis                   ATFFMATGFHGFHVLIGTIFLLVCLFRAIGGDFTPKQHFGFEAAAWYWHF 267
Brucella_abortus                ATFFMATGFHGFHVLIGTIFLLVCLFRAIGGDFTPKQHFGFEAAAWYWHF 267
Mesorhizobium_sp.               ATFFMATGFHGFHVIVGTIFLAVCLLRAMAGQFTPKQHFGFEAAAWYWHF 269
Nitrobacter_winogradskyi        ATFFMATGFHGFHVLVGTIFLIVCLFRANAGHFTPSQHLGFEFAAWYWHF 257
Homo_sapiens                    STFFVATGFHGLHVIIGSTFLTICFIRQLMFHFTSKHHFGFEAAAWYWHF 244
Shewanella_oneidensis           NTFFLLTGFHGMHVTLGTIFLLVLFFRVLKGHFSADKHFAFQAGSWYWHF 276
Shewanella_sp.                  NTFFLLTGFHGMHVTLGTIFLLVLFFRVLKDHFSADKHFVFQAGSWYWHF 276
Burkholderia_phymatum           STFFLLTGFHGFHVFLGGTMLAVVLVRLIRGHFTADHHFAFEGAAWYWHF 270
Mycobacterium_tuberculosis      SVFYLATGFHGLHVTGGLIAFIFLLVRTGMSKFTPAQATASIVVSYYWHF 187
Serratia_proteamaculans         SGFFALVATHGLHVTTGLVWIVIMMIQVSKRGLTSTNKTRLMCLSLFWHF 186
Xylella_fastidiosa              SAFFTLVGTHGLHVASGLLWMLILVIQIVKNGLTPRNSTRLACLSLFWHF 184
Francisella_tularensis          SSFFTLVGTHGLHVSMGLIWIVSMIFQLKKYGMNPMAKTKLTYLGLFWHF 182
Roseiflexus_castenholzii        TTFFVLTGFHGTHVAIGVIWLLSVFFKVRTYPNSPENAMDVEIAGLYWHF 188
Geobacter_metallireducens       SLYYLTVGLHGLHVLIGGTLLAVVAARVGRGTIHAGDFAWLENGALYWHL 184
                                  ::  .. ** **  *   :     :       .         . :**:

Brucella_suis                   VDVVWLFLFFAIYVWGGWGAPMHGG-- 292
Brucella_abortus                VDVVWLFLFFAIYVWGGWGAPMHGG-- 292
Mesorhizobium_sp.               VDVVWLFLFAFIYVWASAGATIAH--- 293
Nitrobacter_winogradskyi        VDVVWLFLFVCIYIWGNGAAAMAHAAH 284
Homo_sapiens                    VDVVWLFLYVSIYWWG----------- 260
Shewanella_oneidensis           VDVVWLCLFIFVYVL------------ 291
Shewanella_sp.                  VDVVWLCLFIFVYVL------------ 291
Burkholderia_phymatum           VDVVWLGLYVVVYWL------------ 285
Mycobacterium_tuberculosis      VDIVWIALFTVIYFIR----------- 203
Serratia_proteamaculans         LDVVWICVFTVVYLLGVMS-------- 205
Xylella_fastidiosa              LDVIWIGVFTIVYLLGAL--------- 202
Francisella_tularensis          LDIVWIFVFSIVYLLGAV--------- 200
Roseiflexus_castenholzii        VDLVWVAIFVLVYLI------------ 203
Geobacter_metallireducens       VDLVWIFIFPLYYLVL----------- 200
                                :*::*: ::   *